Broncos vs. Seahawks prediction, odds, time: 'Thursday Night Football' picks by proven model

SportsLine’s model has revealed its Seattle Seahawks vs. Denver Broncos picks for ‘Thursday Night Football’

The Seattle Seahawks will look to get back on track when they battle the Denver Broncos in a key interconference matchup on 'Thursday Night Football.' Seattle is coming off a hard-fought 32-29 loss to San Francisco on Sunday, while Denver held on for a 23-17 victory over the Los Angeles Chargers. The Seahawks (3-2), who are second in the NFC West, are 1-1 on the road this season. The Broncos (3-2), who are second in the AFC West, are 2-0 on their home field in 2026. Seattle receiver Jaxon Smith-Njigba (ankle) was limited at practice on Tuesday. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55: Kickoff is set for 8:15 p.m.

ET from Empower Field at Mile High in Denver. The latest Seahawks vs. Broncos odds have Seattle as 2.5-point favorites. The over/under for total points scored is 40.5. Before making any Broncos vs. Seahawks picks, be sure to see the 'Thursday Night Football' predictions' from SportsLine's proven model. The model, which simulates every NFL game 10,000 times, is up more than $5,000 for $100 players on betting sites on top-rated NFL picks since its inception. The model entered Week 6 of the 2026 NFL season on a 57-46 run on top-rated picks dating back to 2024.