NFL picks against the spread, Week 6 2026: Expert ATS picks, predictions, prop bets for Sunday, Oct. 18

The SportsLine experts have locked in their top Week 6 picks from this week The Week 6 NFL schedule features top contests such as Bears vs. Falcons, Chargers vs. Chiefs and Bills vs. Raiders as part of the Sunday NFL slate, leading into a Sunday Night Football clash of Cowboys vs. Packers. After five weeks of the 2026 NFL season, SportsLine's team of NFL experts can pull from more reliable team trends and statistics, as well as keep up with the latest injury reports, leading to plenty of confident NFL picks on the Week 6 NFL schedule to use for NFL Week 6 predictions and NFL ATS picks. The latest Week 6 NFL odds list the Chiefs as 8-point favorites against the Chargers, and the Packers are 1-point favorites against the Cowboys on Sunday Night Football with an over/under of 53.5 points, tied for the highest of the Week 6 NFL slate.

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