Rays vs. Guardians prediction, odds, time: 2026 ALCS Game 5 picks by proven model

SportsLine’s model simulated Sunday’s Tampa Bay Rays vs. Cleveland Guardians ALCS Game 5 matchup 10,000 times

The American League Championship Series has been back and forth, with the Cleveland Guardians and Tampa Bay Rays alternating wins ahead of Sunday's Game 5. Cleveland prevailed in Games 1 and 3, with Tampa winning Games 2 and 4 as they enter Game 5 with the series tied 2-2. Parker Messick (12-9, 2.56 ERA) will take the mound for Cleveland, countered by Drew Rasmussen (16-5, 2.67 ERA) of Tampa. Game 6 will take place in Tampa on Monday and a Game 7, if needed, will be held in Sunday, also in Tampa. Visit our Kalshi promo code review and get a $55 trading bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55: First pitch for Game 5 from Progressive Field in Cleveland is set for 5:08 p.m.

ET. The Rays are 7-3 in the regular and postseason versus the Guardians this year. Tampa Bay is a -136 favorite on the money line (risk $136 to win $100), while Cleveland is at +113 in the latest Guardians vs. Rays odds. The over/under is 6.5. Before making any Rays vs. Guardians picks, be sure to see the Rays vs. Guardians predictions and betting advice from SportsLine's proven computer model. SportsLine's model simulates every MLB game 10,000 times and entered the 2026 ALCS on a 31-25 run on all top-rated MLB