Christina Applegate Reveals She Was Misdiagnosed and Does Not Have MS: “I Haven’t Gotten Better … I’m Back at Square One”

Applegate returned to the podcast she co-hosts with Jamie Lynn-Sigler to reveal the health news that is sending her for a loop: "You don't get misdiagnosed and then all of a sudden, I'm better. I haven't gotten better," she shares. "If anything, I've gotten worse in some ways." Christina Applegate returned to her Messy podcast with Jamie Lynn-Sigler to reveal the health news that she does not have MS, but is still getting worse. Christina Applegate returned to her podcast after some time away to reveal that she was misdiagnosed and does not, in fact, have MS. Applegate revealed in a two-part episode of her MeSsY podcast that she co-hosts with Jamie-Lynn Sigler, who has multiple sclerosis (MS), that, in 2021, she was being tested for “everything under the sun,” but not MS right away.

She had brain and spinal MRIs, and a spinal tap, which determined that she had RMS, which was, at the time, “on the low scale.” However, Applegate said she was getting progressively worse. The doctor then showed her the legions on her brain, almost 40, she said, and “that was it. That was my answer to everything that was going on” at the time. Applegate revealed her diagnosis in August 2021, at age 49, sharing publicly that