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USC vs. Wisconsin prediction, pick, odds, spread: Trojans, Badgers look to keep Big Ten hopes alive

No. 16 USC, which has rebounded from the Oregon loss with back-to-back wins, seeks to improve its road record to 3-0 on Saturday night in Wisconsin When you look around the Big Ten these days, there's a lot…
One Place News   •   October 22, 2026   •   Updated October 22, 2026
USC vs. Wisconsin prediction, pick, odds, spread: Trojans, Badgers look to keep Big Ten hopes alive

No. 16 USC, which has rebounded from the Oregon loss with back-to-back wins, seeks to improve its road record to 3-0 on Saturday night in Wisconsin When you look around the Big Ten these days, there's a lot of uncertainty. Nearly half the league is down to its backup quarterback, whether due to injury or by choice. The only undefeated team in the conference is UCLA, while Oregon's conference title hopes are hanging on by a thread. Ohio State just picked up a huge win, but faces the prospect of being without Julian Sayin for the rest of the season. It's chaos, and when chaos is around, there's a chance someone unexpected will emerge and take advantage of it.

So while No. 16 USC's trip to Madison this weekend to face Wisconsin might not be the headliner game of the weekend, it's a chance for two teams to step forward and stake a claim in the conference. USC has won two straight since dropping a game to Oregon, and perhaps most surprisingly, one of those wins has come on the road. The Trojans are 2-0 outside the Coliseum, which has been a serious problem for them during Lincoln Riley's tenure. Now they're back on the road facing a Wisconsin team coming off its first Big Ten loss at UCLA last

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This One Place News story was acquired from cbssports.com. OPN retains the source link and provenance for newsroom review.

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