Colts vs. Vikings odds, picks, prediction, spread: Start time, NFL Week 7 betting preview, best bets

Here’s everything bettors need to know for Colts vs. Vikings in NFL Week 7 action

The Minnesota Vikings look to stay undefeated when they host the Indianapolis Colts in Week 7 of the NFL season. Minnesota has ridden the sport's best scoring defense to a 5-0 record despite some shaky play from quarterback Kyler Murray. Things haven't been as smooth for the Colts, who are 2-4 and just dismissed GM Chris Ballard. Minnesota is a 6.5-point favorite in the latest NFL odds at DraftKingsSportsbook, and the total is 41.5. Kickoff is scheduled for 1 p.m. ET. Target NFL predictions at Kalshi, where new users can get a $55 bonus with the best Kalshi promo code CBSSPORTS55: We'll break down the latest Colts vs. Vikings odds from DraftKings and deliver our best bets for the contest with help from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $5,000 for $100 players on betting sites on top-rated NFL picks since its inception. The model entered Week 7 of the 2026 NFL season on a 58-48 run on top-rated picks dating back to 2024. Anybody following its picks at NFL betting sites could have seen strong returns. The wheels have come off for Indianapolis. Giving the Tennessee Titans their first win of the season was the straw that broke the camel's back for GM Chris Ballard, and it seems