Broncos vs. Cardinals odds, picks, prediction, spread: Start time, NFL Week 7 betting preview, best bets

We have everything bettors need to know before placing any wagers on Sunday The Denver Broncos visit the Arizona Cardinals in an NFL Week 7 matchup on Sunday at State Farm Stadium in Glendale, Ariz. The Broncos (4-2) have won four of their past five games, including a 17-14 overtime victory against the reigning Super Bowl champion Seattle Seahawks on Thursday Night Football in Week 6. The Cardinals (2-4) were 12.5-point road underdogs against the Los Angeles Rams but came away with an 18-16 victory. Sunday's kickoff is set for 4:05 p.m. ET. The Broncos are 4.5-point road favorites in the latest Broncos vs. Cardinals odds at DraftKings Sportsbook, and the Over/Under is 42.5.

Target NFL predictions at Kalshi, where new users can get a $55 bonus with the best Kalshi promo code CBSSPORTS55: We'll break down the latest Broncos vs. Cardinals odds from DraftKings and deliver our best bets for the contest with help from the SportsLine Projection Model. The model, which simulates every NFL game 10,000 times, is up more than $5,000 for $100 players on betting sites on top-rated NFL picks since its inception. The model entered Week 7 of the 2026 NFL season on a 58-48 run on top-rated picks dating back to 2024. Anybody following its picks at NFL betting sites could have seen strong