Pistons vs. Knicks prediction, odds, betting preview, start time: NBA picks, best bets on Tuesday, Oct. 27

Best bets and betting preview for Pistons vs. Knicks on Tuesday The New York Knicks host the Detroit Pistons in an early-season Eastern Conference showdown on Tuesday night, as New York tries to pick up its first win of the season. Meanwhile, Detroit is off to a 3-0 start after beating the 76ers on Sunday. The Knicks are 4.5-point home favorites in the Knicks vs. Pistons odds, while the over/under is 218.5. Pistons center Jalen Duren is out tonight with a hamstring injury. Claim the Kalshi promo code CBSSPORTS55 here now and get a $55 bonus after $25 in trades: Tipoff for Knicks vs. Pistons is set for 8 p.m.

ET at Madison Square Garden. SportsLine's proven computer model and one of its experts have analyzed Pistons vs. Knicks and revealed their Knicks vs. Pistons prediction, and you can also read our NBA betting preview for Tuesday's matchup. Claim the latest Polymarket promo code CBSSPORTS to get a $25 bonus after $10 in trades: It has been a disappointing start to the season for the defending champion Knicks, who have lost three straight games to open the campaign. They fell to the 76ers, Celtics and Magic in a trio of single-digit losses, becoming the first defending champion to start 0-3 since the 2011-12 Mavericks. Jalen Brunson is averaging a team-high