Knicks vs. Pistons prediction, odds, time: 2026 NBA picks for Tuesday, Oct. 27 from advanced model

SportsLine’s model reveals its New York Knicks vs. Detroit Pistons best bets on Tuesday

The New York Knicks will be out for revenge — and seeking their first win — on Tuesday's NBA schedule as they host the Detroit Pistons. Despite winning the title last year, New York went 0-3 versus Detroit as the Pistons were the only Eastern Conference team to not lose to the Knicks. This year, Detroit is off to a 3-0 start, while New York enters in at 0-3, making them just the third defending champion to start the next year winless through three games. Jalen Duren (hamstring) is out for Detroit. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55: Tipoff is at 8 p.m.

ET from Madison Square Garden in New York City. Detroit has won each of the last six regular season matchups. New York is a 3.5-point favorite in the latest Knicks vs. Pistons odds, while the over/under is 218.5. Before making any Pistons vs. Knicks picks, check out the Knicks vs. Pistons predictions from the SportsLine Projection Model. The SportsLine Projection Model simulates every NBA game 10,000 times and has returned nearly $19,000 in profit for $100 players on its top-rated NBA picks since 2018, including five straight seasons of four-digit profit. The model enters Week 2 of the 2026-27 season on a