NBA DFS: Top DraftKings, FanDuel daily Fantasy basketball picks for Thursday, Oct. 22 include Jalen Williams

SportsLine’s Mike McClure, a daily Fantasy pro with more than $2 million in winnings, gives optimal NBA DFS lineup advice for Thurssday

DFS millionaire Mike McClure reveals his daily Fantasy basketball picks for FanDuel and DraftKings on Thursday, Oct. 22 Only two games dot the NBA schedule on Thursday, but there's value in the NBA DFS pool. Cleveland battles LeBron James and the Philadelphia 76ers, while Nikola Jokic and the Denver Nuggets face Shai Gilgeous-Alexander and the Oklahoma City Thunder. Among the other top options for NBA DFS lineups include Tyrese Maxey, James Harden, DeMar DeRozan, Evan Mobley and Isaiah Hartenstein. Jokic is the most expensive player on both DraftKings and FanDuel as the Nuggets and Cavaliers open their 2026-27 seasons. Knowing which players justify their high costs and knowing which are better kept our of daily Fantasy basketball lineups should be a part of your NBA DFS strategy.

Before making any NBA DFS picks, be sure to check out the NBA DFS advice, player rankings, stacks, and top daily Fantasy basketball picks from SportsLine's Mike McClure. McClure is a DFS professional with more than $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account. This allows him to find the best NBA DFS values on sites like DraftKings and FanDuel and create optimal