NFL Week 7 upset alert: Can Giants upset Texans with JJ McCarthy at QB? Can Falcons beat 49ers?

Baltimore and Denver are two other teams firmly at risk of being upset. The NFL is funny sometimes. Just when you think you have everything pegged, the league will rip the carpet right out from under you before you even realize it. On a week-to-week basis, any team appears capable of winning, no matter how bleak things may seem from the outside looking in. Take the Cardinals-Rams games for instance. Los Angeles was dubbed a superteam coming into 2026 and the prohibitive favorite to win the Super Bowl. All the while, Arizona was pinpointed as one of the worst teams in the league and possibly earmarked for the No. 1 overall pick.

What happened on Sunday? The Cardinals rolled into SoFi Stadium and handed us arguably the biggest upset of the season. The only thing that stung about Arizona's stunning victory was that we didn't highlight it in last week's post. I had the Cardinals coverering in my weekly picks column, but that was thinking more along the lines of hitting the backdoor cover late. While we weren't able to sniff out that upset, we did put you on to the Texans taking down the Jaguars in London and the Tennessee Titans taking down the Colts in Indy in last week's piece. We nearly had the Bucs as we win