Oregon vs. UCLA prediction, pick, odds, spread: Bruins looking for signature win against shorthanded Ducks

Dylan Raiola steps in under center for the Ducks as Bob Chesney’s unbeaten Bruins bring a potent ground game to Autzen Stadium with major Big Ten stakes on the line

Dylan Raiola steps in under center for the Ducks as Bob Chesney No. 13 Oregon and No. 21 UCLA are squaring off Saturday at 3:30 p.m. Eastern on CBS in game that will reverberate throughout the Big Ten and beyond. The 3-1 Ducks are already dealing with a thin margin for error as they prepare to host a 4-0 UCLA team that profiles as a potential dark-horse contender under first-year coach Bob Chesney. Both are coming off bye weeks following Week 4 wins, each impressive for different reasons. Oregon took down USC 41-27 on the road and showed an explosive offensive gear, even after losing starting quarterback Dante Moore to a scary injury in the first half.

UCLA turned heads by traveling cross-country for a 54-3 win over Maryland, marked by an all-systems dominance which suggested the Bruins are no joke. While Chesney's first season since arriving from James Madison is off to a perfect start, this marks a new kind of challenge. The Bruins have not played a team currently ranked in the top 60 of the CBS Sports 138 and will be up against Oregon, which entered the season at No. 2 in the AP poll. After a stunning Week 2 loss at Oklahoma State, the Ducks began living up to preseason expectations in their Week 4 win