Week 5 NFL odds, spreads, totals, betting lines, for all 16 games, including Buccaneers-Cowboys, Bears-Packers

The Week 5 NFL schedule is here, featuring pivotal matchups like Cowboys vs. Buccaneers, 49ers vs. Seahawks and Bills vs. Rams The Dallas Cowboys are set to host the Tampa Bay Buccaneers to kick off the Week 5 NFL schedule on Thursday Night Football. According to the latest NFL odds, the Cowboys are favored by 9.5 points at home, while the over/under for total points scored is 47.5. Other notable Week 5 NFL spreads include Eagles vs. Jaguars (-6.5) in London, Raiders vs. Patriots (-3.5), Broncos vs. Chargers (+3.5), 49ers vs. Seahawks (-3) and Bills vs. Rams (-2.5). Bet on every Week 5 NFL game with the latest DraftKings promo code, where new users get $150 in bonus bets after making a $5 wager: Below you'll find the NFL betting odds for every Week 5 matchup.

You can find the SportsLine Projection Model's NFL betting advice for Week 5 here. Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get $55 as a sign-up bonus: Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets: Claim the Fanatics Sportsbook promo code here to get $350 in FanCash: Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook with the bet365 bonus code CBSBET365: Claim the