College football picks, Week 6 best bets by Vegas expert: This parlay could return +600

Thomas Casale has locked in his top college football picks for Week 6 and his CFB parlay could pay out around +600

A couple of undefeated matchups highlight games you can make Week 6 college football best bets on, including an SEC showdown. Georgia vs. Alabama has the Tide as 1.5-point home favorites, per the Week 6 college football spreads. Elsewhere, the Big Ten boasts Indiana vs. Nebraska (+7.5) as the Hoosiers look to start 6-0 for the third straight season. Get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55: Other Week 6 college football lines of note include LSU vs. Kentucky (+8.5), UCLA vs. Oregon (-11.5) on CBS and Paramount+, plus the Red River Rivalry of Texas vs. Oklahoma (+7.5) Before locking in any Week 6 college football picks for those games or others, be sure to see the top Week 6 college football expert picks, predictions and best bets from Thomas Casale.

A frequent guest on national radio and TV shows to discuss college sports, Casale has been sports betting — and winning — for more than 30 years. He swept all three best bets in his column in both Week 4 and Week 5 on SportsLine and has an 8-1 overall record over the last three weeks. Now, he has turned his attention to the Week 6 college football odds and is sharing his top picks. If you parlay these college football betting picks