Villanova vs. Notre Dame betting: Odds, preview, picks, start time for Sunday college basketball from Rome

The Eternal City Tip-Off in Rome pits Villanova against Notre Dame to start the 2026-27 college basketball season The Villanova Wildcats of the Big East will take on the ACC's Notre Dame Fighting Irish in the Eternal City Tip-Off on Sunday, Nov. 1, in the holy city of Rome, Italy, to start the 2026-27 college basketball season. The teams obtained a waiver from the NCAA to start the season a day before the official start of Monday, Nov. 2. The event was set up in part to honor Pope Leo XIV, a 1977 graduate of Villanova, and will be played on All Saints' Day. The Wildcats are 7.5-point favorites in the latest Villanova vs.

Notre Dame odds at DraftKings Sportsbook, and the Over/Under for points scored in the Eternal City Tip-off is 147.5. Sunday's tip-off is set for 9:30 a.m. ET at the Palazzo dello Sport. Bet on college basketball at DraftKings and get $200 in bonuses and three months of NBA League Pass when you spend $5+: We're breaking down the latest Villanova vs. Notre Dame odds from DraftKings Sportsbook and highlighting our best bet. If you're interested in college basketball betting, check out the picks from our experts and the SportsLine Projection Model once the season begins. The Wildcats went 24-8 last season, going 15-5 in the Big