NFL Week 5 picks: Experts face off on 49ers at Seahawks, Falcons vs. Ravens and more

CBS Sports writers Jordan Dajani and Jared Dubin predict this weekend’s top games

CBS Sports writers Jordan Dajani and Jared Dubin predict this weekend We are already five weeks into the 2026 NFL regular season. Can you believe it? This week, the Philadelphia Eagles and Jacksonville Jaguars face off in London, the San Francisco 49ers will play the reigning Super Bowl champion Seahawks in Seattle, and Josh Allen takes on Matthew Stafford on "Monday Night Football." There were 23 games decided by one score over the past two weeks, which is tied for the most in a two-week span in NFL history. A total of 18 games this season were decided by a game-winning score in the final four minutes or in overtime, which is tied for the second-most through Week 4.

The NFL always delivers, and we are expecting more fireworks in Week 5. Which teams should you pick, and which should you fade? CBS Sports writers Jordan Dajani and Jared Dubin are here to break down the biggest games of the weekend. For clarity, lines for these selections were taken on Oct. 6 over at DraftKings Sportsbook. Dajani (Jaguars -7): Our London Jaguars fans must feel proud. The team they've supported for years returns to the United Kingdom as arguably the best team in the AFC, and they will take on a squad that looks like it's flailing. The Eagles blew